Figure 2.

Longitudinal levels of binding and ACE2 competition against SARS-CoV-2 WT and the VoC in paucisymptomatic subjects. IgG binding (antibody level, AU, panels (a–e)) and ACE2 inhibition (percent inhibition, %, panels (f–j)) was measured longitudinally in paucisymptomatic subjects. The panels show cohort running means (thick red line) and their 95% confidence (red shading). Orange shading represents the time period in which subjects were vaccinated. A Kruskal–Wallace test and Dunn’s post-hoc test were performed between all possible combinations longitudinally (* p = 0.05, ** p = 0.01, *** p = 0.001 and **** p = 0.0001). Positivity cut-offs are represented by a dashed black line.