Table 1.
1H and 13C chemical shift values (δ, ppm) of the investigated 4-methylaminorex derivatives in CDCl3 at 25 °C with TMS as internal standard, J-values in Hz.
| Position | 4B-MAR | 4C-MAR | 4F-MAR | |||
|---|---|---|---|---|---|---|
| δC | δH | δC | δH | δC | δH | |
| 2 | 159.3 | - | 159.1 | - | 158.9 | - |
| 4 | 68.6 | 3.87 (p, 6.4) | 68.7 | 3.88 (p, 6.9) | 68.7 | 3.91 (p, 6.8) |
| 5 | 88.2 | 4.87 (d, 6.8) | 88.2 | 4.88 (d, 7.2) | 88.5 | 4.90 (d, 7.2) |
| 2-NH2 | - | 4.82 (brs) | - | 4.54 (brs) | - | 4.34 (brs) |
| 4-CH3 | 21.6 | 1.32 (d, 7.1) | 21.6 | 1.32 (d, 6.4) | 21.6 | 1.32 (d, 6.6) |
| 1′ | 139.1 | - | 138.5 | - | 135.7 (d, 3.2) | - |
| 2′/6′ | 127.3 | 7.20 (d, 8.5) | 127.1 | 7.26 (d, 8.6) | 127.6 (d, 8.3) | 7.31 (dd, 8.8, 5.3) |
| 3′/5′ | 131.9 | 7.50 (d, 8.5) | 128.9 | 7.34 (d, 8.6) | 115.7 (d, 21.6) | 7.03 (t, 8.8) |
| 4′ | 122.2 | - | 134.1 | - | 162.7 (d, 246.8) | - |