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In vitro CsA activity on cytokine production (A), T cell activation marker expression (B), and T cell proliferation (C). All whole blood samples were taken pre-dose, stimulated with PHA, and incubated with a concentration range of CsA (10,000, 3300, 1100, 360, 120 µg/L). Absolute data points (±SD) and logistic regression model are plotted.
