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. 2022 Sep 12;14(9):2016. doi: 10.3390/v14092016

Figure 6.

Figure 6

Characterization of mutant epitope-specific CD8 T cells in convalescent COVID-19 patients. (a) Representative data for the detection of epitope-specific CD8 T cells in HLA-A2+ convalescent COVID-19 patients who recovered from COVID-19 infection at 7 (top) and 50 days (bottom) with tetramers prepared using SARS-CoV-2 epitopes. (b) Overall statistics and comparison of CD8 T cells specific to ancestral and mutant SARS-CoV-2 epitopes in convalescent COVID-19 patients. Variant strain IDs are the same as listed in Table 1. Data shown are the mean ± SD. n = 6 for each group. (c) Fitted curves for ancestral (left) and mutant (right) epitopes at 7 and 50 days after the third dose of vaccination and 7 and 50 days after recovery from COVID-19 infection.