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Solution competition between heparin and sulfated glycans. (A) SPR sensorgrams of MPXV A29–heparin interaction, by competing with PPS or MPS. Concentration of MPXV A29 is 250 nM mixed with 1000 nM of sulfated glycans. (B) Bar graphs (based on triplicate experiments with standard deviation) of normalized MPXV A29 binding preference to surface heparin, by competing with PPS or MPS.
