Table 2.
Summary of kinetic data of MPXV A29 binding with heparin, DS, CSA, and CSE.
| ka (M−1s−1) | kd (s−1) | KD (M) | |
|---|---|---|---|
| Heparin | 2.8 × 104
(±280) * |
7.1 × 10−3
(±5.0 × 10−5) * |
2.6 × 10−7
(±1.7 × 10−8) ** |
| DS | 4.5 × 103 (±54) |
2.8 × 10−3
(±2.6 × 10−5) |
6.2 × 10−7
(±1.7 × 10−9) |
| CSA | 3.7 × 103
(±120) |
3.2 × 10−3
(±5.4 × 10−5) |
8.4 × 10−7
(±7.1 × 10−9) |
| CSE | 4.9 × 103
(±72) |
1.5 × 10−3
(±4.7 × 10−5) |
3.1 × 10−7
(±6.1 × 10−9) |
* The data with (±) in parentheses are the standard deviations (SD) from global fitting of five injections. ** Standard deviation (SD) on triplicate experiments.