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Cell viability in SH-SY5Y cells assessed by MTS assay in SH-SY5Y neuroblastoma cells following 16- and 24-h incubation +/− 80 mM of glutamate and test compound. Reported values represent the average of 12 replicate wells ± SEM. All groups receiving glutamate treatment were significant when compared to control wells without glutamate treatment, designated as 100% viability (p < 0.0001). **** p = 0.0001 vs. vehicle control; *** p = 0.0003 vs. MDL 72527.
