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Compound 6 reduced production of ROS in SH-SY5Y cells following acute excitotoxic stress (8 mM of glutamate exposure) in a dose-dependent manner, as measured by CM-H2DCFDA. Reported values represent the average of 3 or 4 replicates ± SEM. * p = 0.0004; ** p < 0.0001.
