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. 2022 Sep 19;12(9):882. doi: 10.3390/metabo12090882

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A) Pnvf is reduced in children and younger adults with congenital heart disease (CHD) compared to normal referents. (B) Pnvf is reduced in children and younger adults with single ventricle congenital heart disease (CHD) compared to bi-ventricular congenital heart disease. Regions with decreased Pnvf (controlling for age and gender) are mainly concentrated in default mode network (DMN), central executive network (CEN), and salience network (SN) regions. All regions significant at FDR-corrected q < 0.05. Abbreviations: Ventrolateral medial prefrontal cortex (VMPC), Insula (INS), Dorsolateral prefrontal cortex (DLPC), Posterior Cingulate (PCING), Precuneus (PCU), Dorsal Anterior Cingulate Cortex (DACC), Posterior Parietal (PP).