Table 1.
Demographics and clinical information of the participants.
| Parameters | ALS “Advanced” Patients Mean (SD) (n = 6) | ALS “Early” Patients Mean (SD) (n = 9) |
|---|---|---|
| Demographic and clinical measures | ||
| Age | 64.66 (12.20) | 63,92 (10.56) |
| Male/Female | 4/2 | 6/3 |
| Education | 9.17 (4.49) | 8.76 (3.67) |
| Disease duration (months) | 54.33 (43.01) | 38.68 (16. 22) |
| ALSFRS-R score | 32.0 (8.85) | 41.62 (3.60) |
| UMN score | 8.33 (6.77) | 5.34 (2.61) |
| Site of onset | 1 bulbar | 1 bulbar |
| 5 Spinal | 8 Spinal | |
| Phenotype | 2 predominant LMN. | 7 predominant LMN. |
| 1 predominant U.M.N. | 1 predominant U.M.N. | |
| 2 Classic | 1 Classic | |
| Riluzole | 6/6 | 9/9 |
| Neuropsychological parameters | ||
| ECAS test (total score) | 93.67 (14.14) | 93.45 (14.82) |
ALSFRS-R = Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised; ECAS = Edinburgh Cognitive and Behavioral; LMN = lower motor neuron; UMN = upper motor neuron.