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. 2022 Aug 28;14(9):1906. doi: 10.3390/v14091906

Figure 6.

Figure 6

Chemokine receptor profiles for major CD8+ T cell subsets with varying patterns of CD45RA and CD62L expression in acute and convalescent COVID-19 patients. Scatter plots (A–D), (E–H), (I–L) and (M–P) show the percentages of ‘naïve’ (CD45RA+CD62L+), central memory (CM, CD45RA−CD62L+), effector memory (EM, CD45RA−CD62L−), and terminally differentiated CD45RA-positive effector memory (TEMRA, CD45RA+CD62L−) CD8+ T cells, respectively, expressing CXCR5, CXCR3, CCR6, and CCR4, respectively. Black circles denote patients with acute COVID-19 (COV, n = 71); black squares—convalescent COVID-19 individuals (CON, n = 51); white circles—healthy control (HC, n = 46). Each dot represents individual subjects, and horizontal bars depict the group medians and quartile ranges (Med (Q25; Q75). In Figure 6, the statistical analysis was performed with the Mann–Whitney U test.