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(A) TRPV4 expression in blood vessels of tongue tissues with OSCC of animal groups treated with 4NQO. (i) H&E and (ii) immunohistochemistry staining of blood vessels. (B) (iii) H&E and (iv) immunohistochemistry staining of blood vessels in 4NQO group treated with GSK1016790A. Note that GSK1016790A enhanced the TRPV4 expression in blood vessel of cancerous tissue. Scale bar is 50 µm and magnified to 1:1.
