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Effect of dilution with simulated GI fluids on self-nanoemulsifying chewable tablets (SNECT) characteristics.
| Formulation | Dilution Fold | SGF | SIF | ||
|---|---|---|---|---|---|
| ADS | PDI | ADS | PDI | ||
| TDL-SNECT | 10 | 165 ± 8.3 | 0.49 ± 0.04 | 166 ± 7.5 | 0.50 ± 0.04 |
| 100 | 169 ± 7.9 | 0.42 ± 0.03 | 169 ± 8.6 | 0.48 ± 0.05 | |
| 200 | 169 ± 6.6 | 0.41 ± 0.02 | 174 ± 9.9 | 0.44 ± 0.03 | |
| 400 | 173 ± 7.1 | 0.46 ± 0.07 | 176 ± 7.7 | 0.49 ± 0.05 | |
| 800 | 174 ± 8.3 | 0.51 ± 0.05 | 179 ± 8.3 | 0.51 ± 0.02 | |
