| ADMET | Absorption, Distribution, Metabolism, Excretion, Toxicity |
| AlogP | Computationally Derived LogP |
| BEI | Binding Efficiency Index |
| BLI | Biolayer Interferometry |
| bRo5 | Beyond Rule of Five |
| CE | Capilary Electrophoresis |
| ClogP | Computationally Derived LogP |
| CryoEM | Cryo-Electron Microscopy |
| DSF | Differential Scanning Fluorimetry |
| EE | Enthalpic Efficiency |
| FBDD | Fragment-Based Drug Discovery |
| GCI | Grating-Coupled Interferometry |
| GE | Group Efficiency |
| HA | Heavy Atoms |
| HBA | Hydrogen Bond Acceptors |
| HBD | Hydrogen Bond Donors |
| HTS | High Throughput Screening |
| IDP | Intrinsically Disordered Protein |
| ITC | Isothermal Titration Calorimetry |
| LE | Ligand Efficiency |
| LipE | Lipophilic Efficiency |
| LLE | Ligand Lipophilic Efficiency |
| LogP | Logarithm of Octanol/Water Partition Coefficient |
| MST | Microscale Thermophoresis |
| NME | New Molecular Rntities |
| NMR | Nuclear Magnetic Resonance |
| NNH | Number of non-hydrogen atoms |
| NP | Natural Products |
| PAINS | Pan-Assay Interference Compounds |
| PSA | Polar Surface Area |
| QSAR | Quantitative Structure-Activity Relationships |
| Ro3 | Rule of Three |
| Ro5 | Rule of Five |
| ROTB | Rotatable Bonds |
| SBDD | Structure-Based Drug Design |
| SIHE | Size Independent Enthalpic Efficiency |
| SPR | Surface Plasmon Resonance |
| TPSA | Topological Polar Surface Area |
| TSA | Thermal Shift Assay |
| WAC | Weak Affinity Chromatography |