ADMET
|
Absorption, Distribution, Metabolism, Excretion, Toxicity |
AlogP
|
Computationally Derived LogP |
BEI
|
Binding Efficiency Index |
BLI
|
Biolayer Interferometry |
bRo5
|
Beyond Rule of Five |
CE
|
Capilary Electrophoresis |
ClogP
|
Computationally Derived LogP |
CryoEM
|
Cryo-Electron Microscopy |
DSF
|
Differential Scanning Fluorimetry |
EE
|
Enthalpic Efficiency |
FBDD
|
Fragment-Based Drug Discovery |
GCI
|
Grating-Coupled Interferometry |
GE
|
Group Efficiency |
HA
|
Heavy Atoms |
HBA
|
Hydrogen Bond Acceptors |
HBD
|
Hydrogen Bond Donors |
HTS
|
High Throughput Screening |
IDP
|
Intrinsically Disordered Protein |
ITC
|
Isothermal Titration Calorimetry |
LE
|
Ligand Efficiency |
LipE
|
Lipophilic Efficiency |
LLE
|
Ligand Lipophilic Efficiency |
LogP
|
Logarithm of Octanol/Water Partition Coefficient |
MST
|
Microscale Thermophoresis |
NME
|
New Molecular Rntities |
NMR
|
Nuclear Magnetic Resonance |
NNH
|
Number of non-hydrogen atoms |
NP
|
Natural Products |
PAINS
|
Pan-Assay Interference Compounds |
PSA
|
Polar Surface Area |
QSAR
|
Quantitative Structure-Activity Relationships |
Ro3
|
Rule of Three |
Ro5
|
Rule of Five |
ROTB
|
Rotatable Bonds |
SBDD
|
Structure-Based Drug Design |
SIHE
|
Size Independent Enthalpic Efficiency |
SPR
|
Surface Plasmon Resonance |
TPSA
|
Topological Polar Surface Area |
TSA
|
Thermal Shift Assay |
WAC
|
Weak Affinity Chromatography |