Skip to main content
. 2022 Sep 14;14(9):2044. doi: 10.3390/v14092044

Figure 6.

Figure 6

The roles of Arf GTPases in CoV infection. After genome release, MHV will experience RNA replication in the cytoplasm with the help of Sar1 and ARF1 GTPases. After viral replication and assembly, β-coronaviruses such as SARS-CoV-2 and MHV packed by lysosomes may undergo an anterograde movement along microtubules for egress, which is regulated by Arl8b and Rab7 GTPases. Abbreviations—MHV: mouse hepatitis coronavirus; SARS-CoV-2: severe acute respiratory syndrome coronavirus 2.