Table 2.
Adjuvant molecules targeted small GTPases.
| Molecule (Adjuvant) | Targeted Small GTPase | Cell/Animal Type Studied | Reference |
|---|---|---|---|
| CNF1 * | Rac1 and Cdc42 | HEp-2 cell; Females BALB/c Mice | [12] |
| DNT * | Rac1 and Cdc42 | Females BALB/c Mice | [12] |
| Leptin | Rac1 | Dendritic cells (DCs) | [13] |
| Lipophilic statins and bisphosphonates |
Rab5 | B16-OVA, TC-1 and B16-F10; Mice and Cynomolgus Monkeys |
[88] |
| R-naproxen and R-ketorolac |
Rac and Cdc42 | Cell-based and preclinical animal studies have been completed (cell and animal types not reported) | [104] |
* CNF1: cytotoxic necrosis factor 1; DNT: dermal necrosis toxin.