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Regulation of oleic acid synthesis in humans. Oleic acid (MUFA) is synthesized endogenously by the enzyme Strearoyl-CoA Desaturase-1 (SCD1) and introduced with food such as EVOO. SCD1 catalyzes the conversion reaction of saturated fatty acids (SFA) to monounsaturated fatty acids (MUFA); if SCD1 is inhibited, the production of MUFA (Oleic acid) decreases. To prevent oleic acid deficiency, it is important to introduce it through the diet.
