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. 2022 Sep 10;14(18):3749. doi: 10.3390/nu14183749

Table 2.

Main ongoing clinical trials exploring the role of olive oil compounds in the prevention and treatment of cancer patients.

Name of Study and NCT Number Phase Study Arms N° of Patients Study Type Status
Phase 3 Study of Enteral Nutrition Rich in Eicosapentaenoic Acid (EPA) in Patients Receiving Chemotherapy for Gastric Cancer or Colorectal Cancer
NCT01048463 [27]
Phase 3 Placebo Comparator: EN vs. Experimental: ENLDEPA (Nutriall+LDEPA+ Xelox) vs. Experimental: ENHDEPA (nutriall+HDEPA+ Xelox) 90 Interventional Unknown status
A Mediterranean Diet in Colon Cancer Prevention
NCT00475722 [28]
Not Applicable Active Comparator: 1 Healthy Eating vs. Experimental: 2 Mediterranean 120 Interventional Completed
The Effects of EPA on Biomarkers of Growth and Vascularity in Human Colorectal Cancer Liver Metastases (The EPA for Metastasis Trial)
NCT01070355 [29]
Phase 2 Placebo Comparator: Placebo vs Active. Comparator: EPA free fatty acid 88 Interventional Completed

Abbreviations: EN: enteral nutrition; EPA: Eicosapentaenoic Acid; vs.: versus; N°: number.