Extended Data Table 2. Numbers of cells in human and mouse single cell experiments broken down by cluster, depot, BMI/diet, and technology.
Cell counts per cluster for human and mouse data broken down by technology, depot, and BMI/diet.
| Human Cell Numbers | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| VAT | SAT | VAT total |
SAT total |
Total | |||||||
| sNuc | sNuc | Drop | |||||||||
| BMI | < 30 | 30-40 | > 40 | < 30 | 30-40 | > 40 | < 30 | > 30 | |||
| Adipocyte | 5211 | 1011 | 5253 | 7611 | 2847 | 3938 | 0 | 0 | 11475 | 14396 | 25871 |
| ASPCs | 5938 | 1404 | 7304 | 6848 | 2703 | 7329 | 15195 | 5761 | 14646 | 37836 | 52482 |
| Mesothelium | 7773 | 1927 | 20782 | 0 | 0 | 0 | 0 | 0 | 30482 | 0 | 30482 |
| Endothelial | 2351 | 1030 | 2345 | 4231 | 2783 | 2059 | 577 | 107 | 5726 | 9757 | 15483 |
| Lymphatic Endo | 677 | 240 | 1138 | 195 | 130 | 305 | 168 | 48 | 2055 | 846 | 2901 |
| Pericyte | 381 | 109 | 254 | 353 | 132 | 172 | 60 | 3 | 744 | 720 | 1464 |
| Smooth Muscle | 448 | 360 | 423 | 709 | 621 | 237 | 83 | 5 | 1231 | 1655 | 2886 |
| Macrophage | 1908 | 630 | 6328 | 3121 | 1795 | 2871 | 1256 | 403 | 8866 | 9446 | 18312 |
| Monocyte | 98 | 41 | 173 | 187 | 155 | 549 | 359 | 387 | 312 | 1637 | 1949 |
| Dendritic Cell | 125 | 30 | 340 | 169 | 119 | 188 | 756 | 714 | 495 | 1946 | 2441 |
| Mast Cell | 111 | 27 | 139 | 210 | 294 | 298 | 66 | 23 | 277 | 891 | 1168 |
| Neutrophil | 7 | 9 | 4 | 98 | 12 | 14 | 0 | 2 | 20 | 126 | 146 |
| B Cell | 28 | 12 | 39 | 57 | 49 | 188 | 30 | 26 | 79 | 350 | 429 |
| NK Cell | 229 | 92 | 242 | 375 | 279 | 669 | 297 | 446 | 563 | 2066 | 2629 |
| T Cell | 762 | 382 | 1661 | 667 | 510 | 1522 | 977 | 713 | 2805 | 4389 | 7194 |
| Endometrium | 45 | 150 | 114 | 0 | 0 | 0 | 2 | 1 | 309 | 3 | 312 |
| Total | 26092 | 7454 | 46539 | 24831 | 12429 | 20339 | 19826 | 8639 | 80085 | 86064 | 166149 |
| Mouse Cell Numbers | |||||||
|---|---|---|---|---|---|---|---|
| PG | Ing | ||||||
| Chow | HFD | Chow | HFD | PG Total | Ing Total | Total | |
| Adipocyte | 12874 | 5139 | 8645 | 13276 | 18013 | 21921 | 39934 |
| ASPCs | 9928 | 10194 | 16308 | 14797 | 20122 | 31105 | 51227 |
| Mesothelium | 10074 | 4873 | 0 | 0 | 14947 | 0 | 14947 |
| Endothelial | 1521 | 673 | 1141 | 2261 | 2194 | 3402 | 5596 |
| Lymphatic Endo | 678 | 101 | 224 | 173 | 779 | 397 | 1176 |
| Pericyte | 62 | 170 | 56 | 309 | 232 | 365 | 597 |
| Smooth Muscle | 56 | 52 | 30 | 125 | 108 | 155 | 263 |
| Macrophage | 3788 | 35673 | 9370 | 9017 | 39461 | 18387 | 57848 |
| Monocyte | 975 | 2801 | 1286 | 2545 | 3776 | 3831 | 7607 |
| Dendritic Cell | 268 | 688 | 237 | 379 | 956 | 616 | 1572 |
| Mast Cell | 4 | 267 | 13 | 27 | 271 | 40 | 311 |
| Neutrophil | 23 | 9 | 8 | 7 | 32 | 15 | 47 |
| B Cell | 301 | 594 | 28 | 279 | 895 | 307 | 1202 |
| NK Cell | 110 | 215 | 67 | 282 | 325 | 349 | 674 |
| T Cell | 266 | 472 | 69 | 479 | 738 | 548 | 1286 |
| Male Epithelial | 3463 | 36 | 19 | 329 | 3499 | 348 | 3847 |
| Female Epithelial | 76 | 45 | 6331 | 3135 | 121 | 9466 | 9587 |
| Total | 44467 | 62002 | 43832 | 47420 | 106469 | 91252 | 197721 |