Table 3.

References dealing with organic NPs@RB, including the type of NPs, as well as their size, excitation wavelength, type of detection of ¹O₂, the type of coupling between the NPs and the RB, and the type of biological experiments performed.

PDT Organic NPs
References	Type of NPs	Size of NPs (nm)	Irradiation Conditions	Type of 1O2 Detection	Type of Coupling between NPs and RB	Biological Tests/In Vitro		Biological Test/In Vivo
						Cells Used	Results	Mice Used	Results
[72]	UCNP/PAH/HA-RB	30.34	980 nm, 1.5 mW/cm2, 30 min	nd	Covalent	NIH3T3	Cytotoxicity (+)	nd	nd
[78]	POEGMA-b-P(HPMA-co-RBMA)	52	590–595 nm, 0.2 mW/cm2, 15 min	ADPA	Covalent	HCT116 K562	Cytotoxicity (+)	nd	nd
[70]	RB-BTSA	109 ± 5	490 nm, 30–135 J/cm2, 5–30 min	TMP–OH	Encapsulation	HeLa	Cytotoxicity (+)	nd	nd
[73]	PLGA-NP-RB	28	520 nm, 200 mW/cm2, 30 min	nd	Encapsulation	MCF-7 HeLa	Cytotoxicity (+)	H22 tumor-bearing mice	PDT (+)
[71]	PVK@C153@RB	340	No biological test	2-chlorophenol	Encapsulation	nd	nd	nd	nd
[75]	NaYF4:Er3+,Yb3+ NPs@SPAN-20 micelles@RB@ TOPO@Cremophor@PLGA copolymer	150	980 nm, 10 J/cm2, 6.2 W/cm2, 5 min	nd	Encapsulation	Me-45 MeWo HaCaT	Cytotoxicity (+)	Melanoma cells innoculated on monoclonal mouse	PDT (+)
[74]	HBNCs@RB	220	632 nm, 15 mW/cm2, 60 min	DCFH-DA,	Encapsulation	Tramp-C1	Cytotoxicity (+)	nd	nd
[69]	PAPAM dendrimers G 2.5-RB	20	150 W xenon lamp 540 nm, 10 min	Iodure reaction	Covalent	DLA	Cytotoxicity (+)	nd	nd
[77]	polypeptide C18GR7RGDS	17.28	808 nm, 1.5 W/cm2, 3 min	DPBF	Encapsulation	B16 HeLa	Cytotoxicity (+)	nd	nd
[76]	BP-CDPNP-RB	280	Two photons (810 nm, 245 mW/cm2, 20 min	ABDA	Encapsulation	MCF-7	Cytotoxicity (+)	nd	nd
[77]	PARN@RB	17.28	808 nm, 1.5 W/cm2, 3 min	DPBF DCF-DA	Encapsulation	B16	Cytotoxicity (+)	HeLa tumor-bearing mice	PDT (+)

nd: not determined; cytotoxicity (+): induced tumor cell death in vitro; PDT (+): induced tumor death in vivo.