Table 4.
References dealing with gold NPs@RB, including the type of NPs, along with their size, excitation wavelength, type of detection of 1O2, the type of coupling between the NPs and the RB, and the type of biological experiments performed.
| PDT Gold NPs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| References | Type of NPs | Size of NPs (nm) |
Irradiation Conditions | Type of 1O2 Detection | Type of Coupling between NPs and RB | Biological Tests/In Vitro | Biological Test/In Vivo | ||
| Cells Used | Results | Mice Used | Results | ||||||
| [84] | AuNPs-RB | AuNPs-RB complexes: Electrostatic (53) Covalent (49) |
500 nm, 5 J/cm2 | nd | Covalent | Vero HeLa |
Affinity (+) | nd | nd |
| [85] | Gold NPs@RB@DOX | 124.6 | 532 nm, 14.3 mW/cm2, 6 min | SOSG | Encapsulation | HCT116 MCF-7 CCD 841 CoN |
Cytotoxicity (+) | nd | nd |
| [86] | CTO-RB-AuNR | 0.273 | 980 nm, 1.5 W/cm2, 6 min | DPBF | Covalent | Hep G2 | Cytotoxicity (+) | nd | nd |
| [83] | AuNRs@RB | 13 ± 2 | PDT: 532 nm, 1.76 W/cm2, 10 min PTT: 810 nm NIR light, 8.16 W/cm2, 5 min |
ABDA | Covalent | Cal-27 | Cytotoxicity (+) | Male Syrian Golden hamsters with oral carcinomas | PDT (+) |
nd: not determined; affinity (+): induced the affinity to tumor cells; cytotoxicity (+): induced tumor cell death in vitro; PDT (+): induced tumor death in vivo.