Table 5.
PDT Polymer Dots NPs | |||||||||
---|---|---|---|---|---|---|---|---|---|
References | Type of NPs | Size of NPs (nm) |
Irradiation Conditions | Type of 1O2 Detection | Type of Coupling between NPs and RB | Biological Tests/In Vitro | Biological Test/In Vivo | ||
Cells Used | Results | Mice Used | Results | ||||||
[89] | Pdots-RB with: PEG350-PE, PEG2000-PE, PEG5000-PE | PEG350-PE: 43 ± 9 PEG2000-PE: 77 ± 0.3 PEG5000-PE: 60 ± 0.15 |
473 nm, 0.15 mJ/cm2, between 1 h and 4 h | DMA | Encapsulated in the coating of Pdots | MCF-7 | Cytotoxicity (+) | nd | nd |
[90] | CQDS-RB | CQDs-RB: 33.1 ± 8.7 CQDs: 2.1 ± 0.3 |
532 nm, 20 mW/cm2, 30 min | SOSG | Covalent | MCF-7 | Cytotoxicity (+) | nd | nd |
nd: not determined; cytotoxicity (+): induced tumor cell death in vitro; PDT (+): induced tumor death in vivo.