Table 8.
References dealing with polymer NPs@RB under X-rays, including the type of NPs, along with their size, excitation wavelength, type of detection of 1O2, the type of coupling between the NPs and the RB, and the type of biological tests performed.
| X-PDT Polymer NPs | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| References | Type of NPs | NPs Size (nm) |
Irradiation Conditions | Type of 1O2 Detection | Type of Coupling NPs-RB | Biological Tests/In Vitro | Biological Test/In Vivo | ||
| Cells | Results | Mice Used | Results | ||||||
| [110] | Gadolinium (Gd)–RB coordination polymer nanodots (GRDs) | 3.3 ± 0.8 | In vitro: 532 nm, 30 mW/cm2, 5 min; 1 Gy In vivo: 532 nm, 140 mW/cm2, 15 min; 1 Gy |
SOSG | Coordination | 4T1 | Cytotoxicity (+) | BALB/c mice, 4T1-tumor-bearing mice | PDT (+) |
| [109] | POMo@CS–RB | 80 | 2 Gy/min (160 kV) | SOSG | Adsorption | 4T1 | Cytotoxicity (+) | BALB/c mice, 4T1-tumor-bearing mice | PDT (+) |
| [108] | Ln NPs-PEG-RB | 4 | 2 Gy (150 kV) | nd | Covalent | nd | nd | B16 murine mela noma cells | PDT (+) |
nd: not determined; cytotoxicity (+): induced tumor cell death in vitro; PDT (+): induced tumor death in vivo.