Table 9.
References dealing with nanocomposites@RB under X-ray, including the type of NPs, along with their size, excitation wavelength, type of detection of 1O2, type of coupling between the NPs and the RB, and the types of biological tests performed.
| X-PDT Nanocomposites | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| References | Type of NPs | Size of NPs (nm) |
Irradiation Conditions | Type of 1O2 Detection | Type of Coupling NPs-RB | Biological Tests/In Vitro | Biological Test/In Vivo | ||
| Cells Used | Results | Mice Used | Results | ||||||
| [112] | β-NaGdF4:Tb3+-RB | 25.6 | 80 kV, 0.5 mA (0,05–2 Gy), 20 min | DPBF | Covalent | HepG2 | Cytotoxicity (+) | Nude Mice with subcutaneous HepG2 xenografts | PDT (+) |
| [111] | β-NaGdF4:Tb3+-RB | 10 | 80 kV, 0.5 mA and 45 cm distance (1.17 Gy/h) | DPBF | Covalent | HepG2 | Cytotoxicity (+) | Female BALB/c nude mice | PDT (+) |
| [113] | PEG-capped GdF3:Tb3+@RB nanocomposites | Length: 250 Width: 60 |
136 mGy/4 min | nd | Adsorption | nd | nd | BALB/c (ca. 3 months age, weight 34–35 g) male mice | PDT (+) |
nd: not determined; cytotoxicity (+): induced tumor cell death in vitro; PDT (+): induced tumor death in vivo.