Table 10.
X-PDT Lanthanide@MOF, Nanoprobes, Nanophosphors, ScNPs@RB | |||||||||
---|---|---|---|---|---|---|---|---|---|
Reference | Type of NPs | Size of NPs (nm) |
Irradiation Conditions | Type of 1O2 Detection | Type of Coupling NP-RB | Biological Tests/In Vitro | Biological Test/In Vivo | ||
Cells Used | Results | Mice Used | Results | ||||||
[118] | SNPs@Zr-MOF@RB- SNPs | 30 | 45 kV (0, 3, 6, 9, 12, 15 min). | DPBF | Covalent | 4T1 | Cytotoxicity (+) | 4T1 tumor-bearing BALB/c mice) | PDT (+) |
[114] | ScNPs: LaF3:Tb-RB | 38.9 | 75 kV, 2.0 mA | DPBF | Encapsulation | nd | nd | nd | nd |
[117] | NaGdF4@NaGdF4:Tb@NaYF4 (CSS)@RB@cRGD | 18.8 | 4 Gy/min | DPBF | Covalent | U87MG HepG2 NIH-3T3 |
Cytotocity (+) | nd | nd |
nd: not determined; cytotoxicity (+): induced tumor cell death in vitro; PDT (+): induced tumor death in vivo.