Table 1.
Ongoing clinical trials for use of mushrooms in cancer treatment.
| Mushroom | Cancer | Phase | Study Status | Active Compound/s | Identifier | Investigator |
|---|---|---|---|---|---|---|
| Agaricus bisporus | Breast cancer, cancer survivors | Phase 1 | Completed | Polysaccharides, lectin | NCT00709020 | Shiuan Chen |
| Agaricus bisporus | Prostate cancer | Phase 1b | completed | Polysaccharides, lectin | NCT00779168 | W. Twardowski |
| Agaricus blazei Murill (AndoSan) | Multiple myeloma | Phase 2 | Completed | Agaricus polysaccharides | NCT00970021 | Jon-Magnus Tangen |
| Lentinula edodes | Prostate cancer | Not mentioned | Completed | Genistein Combined Polysaccharide (GCP) | NCT00269555 | Robert Hackman |
| Lentinula edode | Hepatocellular Carcinoma and Hepatitis B and C Infection | Not mentioned | Completed | Arabinoxylan extracted from rice bran treated enzymatically with extract from Lentinula edode | NCT01018381 | Mai Hong Bang |
| Grifola frondosa | Lung Neoplasms and Breast Carcinoma | Phase 1 | Completed | Polysaccharides | NCT02603016 | Shunchang Jiao |
| Omphalotus illudens | Thyroid Cancer | Phase 2 | Completed | A semisynthetic derivative of illudin S | NCT00124527 | Eisai Inc. |
| Omphalotus illudens | Recurrent or Metastatic Gastric Cancer | Phase 2 | Completed | A semisynthetic derivative of illudin S | NCT00062257 | Winnie Yeo |
| Omphalotus illudens | Recurrent or Persistent Epithelial Ovarian Cancer | Phase 2 | Completed | A semisynthetic derivative of illudin S | NCT00019552 | Gisele A. Sarosy |
| Trametes versicolor | Breast cancer | Phase 1 | Completed | Krestin, PSK, PSP | NCT00680667 | Carolyn Torkelson |