nAChRs	Nicotinic acetylcholine receptors
PK	pharmacokinetics
PopPK	population pharmacokinetics
PD	pharmacodynamics
CI	confidence interval
AUC	area under the curve
CL	clearance
Vz	the volume of distribution during the terminal elimination phase
Tmax	the peak concentration time
Cmax	peak concentration
t1/2	terminal half-life
WT	body weight
NLME	nonlinear mixed-effects model
OFV	objective function value
AIC	Akaike Information Criterion
BIC	Bayesian Information Criterion
VPC	visual predictive check
RED	Rapid Equilibrium Dialysis
PI	prediction intervals
PRED	population predicted concentrations
IPRED	individual predicted concentrations
NCA	noncompartmental analysis