Table 2.
Scientific literature mean concentrations of biomolecules with 1H NMR resonances located in or close to the APP (1.96–2.10 ppm) regions of high-resolution spectra of human blood and saliva (Figure 4). a Ranges of mean values obtained from healthy control data were obtained from the Human Metabolome Database [101]. b Total N-acetylneuraminate level, including both APP and low-molecular-mass forms. Abbreviations: n-av, data not available.
Metabolite | Blood a | Saliva a |
---|---|---|
‘Free’ N-Acetylneuraminate | 0.6–2.0 μmol./L | 12.5–41.0 μmol./L |
Total N-Acetylneuraminate b | 1.25–2.50 mmol./L | n-av |
‘Free’ N-Acetylglucosamine | 108 ± 67 nmol./L | n-av |
Glutamate | 24–177 μmol./L | 12–14 μmol./L |
Glutamine | 390–905 μmol./L | 5–42 μmol./L |
Proline | 111–259 μmol./L | 6–158 μmol./L |
Hydroxyproline | 13–40 μmol./L | 0.4–1.5 μmol./L |
Lysine | 105–441 μmol./L | 2–59 μmol./L |