Figure 1.

(A) Individual patient weight loss data for all 12 patients. Mean weight loss was 38.4 lbs (17.4 kg) among the 10 patients enrolled at 24 weeks, with a range of 15.2 to 58.3 lbs (6.9 to 26.4 kg) lost. All patients lost weight. (B) Reduction in the 10-year risk of experiencing a major adverse cardiovascular event as determined by the American College of Cardiology and American Heart Association calculator. The mean relative risk reduction was 44%, corresponding to an absolute mean risk reduction of 4.04%. Vertical light blue bars represent the 25th to 75th percentile changes derived from the violin box-and-whisker plot provided in Supplementary Materials Figure S1.