Table 1.

Fluorescent substrates and ABC inhibitors for efflux analysis.

	ABCB1	ABCC1	ABCG2
FLUORESCENT SUBSTRATE	Rhodamine 123	CFDA	Mitoxantrone
SELECTIVE INHIBITOR	Zosuquidar	MK-571	Ko-143
ATPASE ACTIVITY INHIBITOR	Vanadate
ATP DEPLETION	Sodium azide, dinitrophenol, CCCP
THIOL DEPLETION		Iodoacetic acid, N-ethylmaleimide, Buthionine sulfoximine

CCCP: Carbonyl cyanide m-chlorophenyl hydrazine; MK-571: L-660711, 5-(3-(2-(7-Chloroquinolin-2-yl)ethenyl)phenyl)-8-dimethylcarbamyl-4,6-dithiaoctanoic acid; Ko143: (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino [1′,2′:1,6]pyrido [3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester.