Table 2.
T. cruzi ABC proteins.
| Nomenclature | T. cruzi Gene ID | NCBI Reference Sequences | Location | Putative Protein Length | T. cruzi Strain | Alias |
|---|---|---|---|---|---|---|
| ABCA1 | TcCLB.504881.50 * | XP_809857 | TcChr27 | 1750 | CL Brener Esmeraldo-like | |
| TcCLB.510045.20 * | XP_806887 | TcChr27 | 967 | CL Brener Non-Esmeraldo-like | ||
| ABCA2/4 | TcCLB.507099.80 (a) | XP_817325 | TcChr14 | 1836 | CL Brener Esmeraldo-like | |
| ABCA3/5 | TcCLB.504149.20 * (b) | XP_818098 | TcChr27 | 1750 | CL Brener Esmeraldo-like | ABC1 [94] |
| TcCLB.503573.9 * (c) | XP_803907 | TcChr27 | 967 | CL Brener Non-Esmeraldo-like | ||
| ABCA10 | TcCLB.510149.80 * | XP_813909 | TcChr36 | 1865 | CL Brener Esmeraldo-like | |
| TcCLB.506989.30 * | XP_818638 | TcChr36 | 1866 | CL Brener Non-Esmeraldo-like | ||
| ABCA11 | TcCLB.511725.80 | XP_818719 | TcChr35 | 2260 | CL Brener Non-Esmeraldo-like | |
| ABCB1 | TcCLB.507093.260 | XP_820554 | TcChr39 | 661 | CL Brener Esmeraldo-like | |
| ABCB3 | TcCLB.511537.8 * |
XP_806158 XP_809384 |
TcChr35 | 537 | CL Brener Esmeraldo-like | |
| TcCLB.511021.70 * | XP_811319 | TcChr35 | 735 | CL Brener Non-Esmeraldo-like | ||
| ABCC1/2 | TcCLB.506417.10 (d) pseudogene |
- | ? | 1577 | CL Brener | Tcpgp2 [86] |
| ABCC6 | TcCLB.509007.99 pseudogene |
- | TcChr31 | 1425 | CL Brener Esmeraldo-like | |
| TcCLB.507079.30 * | XP_805658 | TcChr31 | 388 | CL Brener Esmeraldo-like | ||
| TcCLB.457101.30 * | XP_805394 | ? | 253 | CL Brener | ||
| TcCLB.508965.14 * | XP_815145 | TcChr31 | 765 | CL Brener Non-Esmeraldo-like | Tcpgp1 [86] | |
| ABCC9 | TcCLB.510231.29 * | XP_805357 | TcChr34 | 854 | CL Brener Esmeraldo-like | |
| TcCLB.447255.29 * | XP_803480 | TcChr34 | 220 | CL Brener Esmeraldo-like | ||
| TcCLB.506559.100 * | XP_821792 | TcChr34 | 1472 | CL Brener Non-Esmeraldo-like | ||
| ABCD1 | TcCLB.506925.530 | XP_821597 | TcChr39 | 664 | CL Brener Esmeraldo-like | |
| ABCD2 | TcCLB.508927.20 * | XP_804559 | TcChr31 | 674 | CL Brener Esmeraldo-like | |
| TcCLB.509237.30 * | XP_814630 | TcChr31 | 674 | CL Brener Non-Esmeraldo-like | ||
| ABCD3 | TcCLB.510431.150 | XP_819234 | TcChr39 | 635 | CL Brener Esmeraldo-like | |
| ABCE1 | TcCLB.508637.150 * | XP_815243 | TcChr10 | 647 | CL Brener Non-Esmeraldo-like | |
| TcCLB.511913.9 pseudogene |
- | TcChr10 | 418 | CL Brener Non-Esmeraldo-like | ||
| TcCLB.464879.9 * | XP_802148 | TcChr10 | 339 | CL Brener Non-Esmeraldo-like | ||
| ABCF1 | TcCLB.504867.20 * | XP_812776 | TcChr36 | 723 | CL Brener Esmeraldo-like | |
| TcCLB.510943.80 * | XP_817081 | TcChr36 | 723 | CL Brener Non-Esmeraldo-like | ||
| ABCF2 | TcCLB.508897.30 | XP_810886 | TcChr40 | 594 | CL Brener Non-Esmeraldo-like | |
| ABCF3 | TcCLB.509105.130 | XP_814891 | TcChr37 | 673 | CL Brener Non-Esmeraldo-like | |
| ABCG1/2 | TcCLB.506249.70 * (e) | XP_806666 | TcChr37 | 665 | CL Brener Esmeraldo-like | |
| TcCLB.508231.190 * (f) | XP_818614 | TcChr37 | 665 | CL Brener Non-Esmeraldo-like | ABCG1 [114] | |
| ABCG3 | TcCLB.506249.70 * (e) | XP_806666 | TcChr37 | 665 | CL Brener Esmeraldo-like | |
| TcCLB.508231.190 * (f) | XP_818614 | TcChr37 | 665 | CL Brener Non-Esmeraldo-like | ||
| ABCG4 | TcCLB.506579.10 * | XP_811527 | TcChr7 | 700 | CL Brener Esmeraldo-like | |
| TcCLB.507241.39 * | XP_806410 | TcChr7 | 290 | CL Brener Non-Esmeraldo-like | ||
| ABCG5 | TcCLB.504425.70 * | XP_813191 | TcChr22 | 1171 | CL Brener Esmeraldo-like | |
| TcCLB.509331.200 * | XP_816786 | TcChr22 | 1170 | CL Brener Non-Esmeraldo-like | ||
| ABCG6 | TcCLB.507681.100 | XP_818599 | TcChr4 | 682 | CL Brener Non-Esmeraldo-like | |
| ABCH1 | TcCLB.510381.20 * | XP_807302 | TcChr27 | 303 | CL Brener Esmeraldo-like | |
| TcCLB.506905.40 * | XP_806924 | TcChr27 | 303 | CL Brener Non-Esmeraldo-like | ||
| ABCH2 | TcCLB.509669.30 * | XP_816112 | TcChr36 | 318 | CL Brener Esmeraldo-like | |
| TcCLB.509617.80 * | XP_809836 | TcChr36 | 318 | CL Brener Non-Esmeraldo-like | ||
| ABCH3 | TcCLB.511753.100 * | XP_812902 | TcChr32 | 496 | CL Brener Esmeraldo-like | |
| TcCLB.511501.30 * | XP_805965 | TcChr32 | 502 | CL Brener Non-Esmeraldo-like | ||
| OTHERS | TcCLB.506529.160 * | XP_821943 | TcChr6 | 937 | CL Brener Esmeraldo-like | |
| TcCLB.510885.70 * | XP_816152 | TcChr6 | 937 | CL Brener Non-Esmeraldo-like | ||
| OTHERS | TcCLB.508809.30 * | XP_809200 | TcChr23 | 1241 | CL Brener Esmeraldo-like | |
| TcCLB.506619.90 * | XP_812627 | TcChr23 | 1241 | CL Brener Non-Esmeraldo-like | ||
| OTHERS | TcCLB.507105.70 * | XP_811423 | TcChr35 | 1027 | CL Brener Esmeraldo-like | |
| TcCLB.506817.20 * | XP_809803 | TcChr35 | 999 | CL Brener Non-Esmeraldo-like |
Subfamily names follow the HUGO nomenclature, according to Leprohon et al. (2006) [93]. Gene accession numbers and other information was retrieved from TriTrypDB (tritrypdb.org) and GeneDB database (http://www.genedb.org/Homepage accessed on 10 July 2022). Letters after gene accession numbers indicate genes that present more than one nomenclature due to similar phylogeny to different L. major and T. brucei genes. Asterisks represent gene fragments of alleles that represent the same T. cruzi ORF. (-) represents that the gene ID does not have a protein sequence registered in the NCBI. (?) represents that the gene ID does not have a T. cruzi chromosomal location in the TriTrypDB.