Table 2.
Odds ratios and likelihood ratios of polymorphisms under consideration.
| Gene/Polymorphism | OR | 95% CI for OR |
Post Risk |
|---|---|---|---|
| Dopamine D1 Receptor (DRD1): rs4532—risk allele G * | 1.77 | (1.01, 3.10) | - |
| Dopamine D2 Receptor (DRD2): rs1800497—risk allele A1 | 1.45 | (1.15, 1.90) | 0.12 |
| Dopamine D3 Receptor (DRD3): rs6280—risk allele C (Ser9Gly) | 3.37 | (1.54, 7.40) | 0.20 |
| Dopamine D4 Receptor (DRD4): rs1800955—risk allele C (48bp repeat VNTR) | 1.56 | (1.04, 2.36) | 0.10 |
| Dopamine Transporter Receptor (DAT1): SLC6A3 3′-UTR—risk allele A9 (40bp repeat VNTR) | 1.18 | (1.00, 1.45) | 0.10 |
| Catechol-O-Methyltransferase (COMT): rs4680—risk allele G (Val158Met) | 1.43 | (0.98, 2.10) | 0.083 |
| µ-Opioid Receptor (OPRM1): rs1799971—risk allele G (A118G) | 1.47 | (1.00, 2.18) | 0.13 |
| γ-Aminobutyric Acid (GABA) A Receptor, -3 Subunit (GABRB3): CA repeat—risk allele 181 | 0.33 | (0.14, 0.79) | 0.06 |
| Monoamine Oxidase A (MAO-A): 3′ 30bp VNTR-risk allele 4R DNRP | 0.62 | (0.15, 2.63) | 0.05 |
| Serotonin Transporter Receptor (5HTT) Linked Promoter Region (5HTTLPR) in SLC6A4: rs25531—risk allele S′ | 1.23 | (1.07, 1.40) | 0.10 |
* Not enough data. It is noteworthy to point out that for each gene polymorphism, the number of cases and controls has been indicated in Table 1.