Figure 6.

(a) Evaluation of cytotoxicity of PCN−222 and PCN−222@ICG to PC 12 cells. (b) PC 12 cell viability was rescued in the presence of Aβ₄₂ at a concentration of 25 µM when treated with photo-activated PCN−222 and PCN−222@ICG. Each group contained three technical replicates. (c) Live/dead staining of PC 12 cells co-cultured with native Aβ₄₂ and Aβ₄₂ treated with photo-activated PCN−222 and PCN−222@ICG. Scale bar: 200 µm (NIR laser irradiation is 808 nm with a power density of 0.6 W cm⁻²). A total of 25 µM of Aβ₄₂ was used throughout the cell studies.