Table 2.
Semen and hormonal characteristics of men stratified on various CAG categories in the entire Russian study population.
| Parameter | CAG Category (n = 1313) | ||
|---|---|---|---|
| CAG ≤ 19 (Short, n = 95) |
20 ≤ CAG ≤ 24 (Medium, n = 1023) |
CAG ≥ 25 (Long, n = 195) |
|
| Semen volume (mL) | 3.6 (1.6) | 3.5 (1.6) | 3.5 (1.6) |
| Total sperm count (×106/ejaculate) | 188.7 (131.5) a | 170.4 (167.7) ab | 158.6 (203.4) b |
| Sperm concentration (×106/mL) | 55.7 (40.1) a | 49.7 (39.6) ab | 44.8 (41.0) b |
| Progressive motility (%) | 51.3 (23.2) a | 43.1 (26.8) b | 39.9 (27.0) b |
| Normal morphology (%) | 7.9 (2.6) a | 6.5 (3.0) b | 6.4 (3.1) b |
| LH (IU/L) | 3.7 (1.6) | 3.6 (1.6) | 3.8 (1.7) |
| FSH (IU/L) | 4.7 (3.1) | 4.1 (3.9) | 4.4 (3.3) |
| Testosterone (nmol/L) | 19.1 (6.24) | 20.8 (7.7) | 21.3 (7.9) |
| Estradiol (nmol/L) | 0.19 (0.05) a | 0.21 (0.08) ab | 0.21 (0.06) b |
| Inhibin B (pg/mL) | 165.9 (64.2) | 178.5 (66.5) | 169.1 (68.0) |
The data are presented as mean (SD). Abbreviations: LH, luteinizing hormone; FSH, follicle-stimulating hormone. The entire study population was divided into three parts according to the CAG repeat length categories: “short”, “medium” and “long” based on the calculated numbers of CAG repeats. a,b comparisons with various superscript indicators within the variable are significant (p < 0.05).