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. 2022 Sep 23;12(9):e1045. doi: 10.1002/ctm2.1045

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© 2022 The Authors. Clinical and Translational Medicine published by John Wiley & Sons Australia, Ltd on behalf of Shanghai Institute of Clinical Bioinformatics.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Transcriptome‐wide studies of NAT10 Knockdown MCF7 cells. (A) Heatmap showing expression pattern of genes in MCF7 post transfected with NAT10 siRNA. (B) Scattered plot of deferentially genes of siNAT10 vs. siC in RNA‐seq. (C) Volcano plot showing positions of differentially upregulated and downregulated genes in MCF7 post transfected with NAT10 siRNA. (D) Bubble plot demonstrating the KEGG pathway analysis of MCF7 post transfected with NAT10 siRNA. (E) Network analysis of fatty acid metabolic genes. (F) Validation of the expression levels of fatty acid metabolic genes with RT‐PCR. Bars are represented as mean ± SEM (n = 3). *p < .05; **p < .01; ***p < .001; and ns > .05.