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. 2022 Aug 24;14(9):1766. doi: 10.3390/pharmaceutics14091766

Table 5.

Differences in routes of administration and dosing of infliximab (IFX) and adalimumab (ADL) in CD and UC [78,92].

Biologics Route Induction Dose (CD and UC) Maintenance Dose (CD and UC)
IFX i.v.
  • 5 mg/kg;

Weeks: 0, 2, 6.
  • 5–10 * mg/kg;

Every 8 weeks.
ADL s.c.
  • 160 mg day 1, and 2;

+ 80 mg on day 15.
or
  • 80 mg

Days: 1, 2, 15.
  • 40 mg

Every 2 weeks **.
* Higher dose is recommended in the case of
unsustained response to IFX
** Initial start on day 29

i.v.—intravenous route; s.c.—subcutaneous route; CD—Crohn’s disease; UC—ulcerative colitis.