. 2022 Sep 8;14(18):3758. doi: 10.3390/polym14183758

Table 3.

Best-fitted model for all three dependent responses (particle size, zeta potential, and entrapment efficiency of CUR/LCSNPs).

Response	Model	R-Squared (r²)	Adjusted r²	Predicted r²	Std. Dev.	%CV	Adequate Precision	Remarks
Particle size (nm)	Linear	0.9513	0.9401	0.9010	6.86	-	-	-
	Second order (2FI)	0.9206	0.8730	0.6111	11.19	-	-	-
	Quadratic	0.9984	0.9834	0.9389	4.57	2.44	47.4997	Suggested
Zeta potential (mV)	Linear	0.9481	0.9360	0.9028	1.41	-	-	-
	Second order (2FI)	0.9513	0.9220	0.7981	1.55	-	-	-
	Quadratic	0.9896	0.9762	0.9411	0.86	3.04	28.75	Suggested
%EE	Linear	0.8778	0.8229	0.6338	3.08	-	-	-
	Second order (2FI)	0.8643	0.8429	0.6580	2.83	-	-	-
	Quadratic	0.9837	0.9670	0.9378	0.88	1.19	14.20	Suggested