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. 2022 Sep 9;58(9):1250. doi: 10.3390/medicina58091250

Table 1.

Comparison of variables between types of twin zygosity according to age.

Original Adjusted by Age
Zygosity MZ DZ p-Value MZ DZ p-Value
n 40 32 40 32
Gender [n] male 20 16 1 20 16 1
Age [years] (SD) 61.10 (8.74) 63.19 (13.16) 0.423 61.10 (8.74) 63.19 (13.16) 0.423
Brain
Volume
[z-score]
(95% CI)
Cerebellum Posterior Lobe left −0.20 [−1.90, 0.62] −0.87 [−1.67, −0.14] <0.001 1.15 [−0.89, 2.65] 0.81 [−0.58, 1.92] 0.063
Temporal Lobe −0.12 [−1.20, 0.81] −0.55 [−1.15, 0.20] <0.001 1.00 [−0.40, 2.25] 0.72 [−0.80, 2.03] 0.065
Limbic Lobe −0.21 [−1.12, 1.26] −1.21 [−2.23, 0.13] <0.001 1.28 [−0.18, 2.52] 0.19 [−1.40, 3.21] <0.001
Frontal Lobe −0.04 [−1.10, 0.71] −0.77 [−1.68, 0.44] <0.001 1.21 [−0.01, 3.32] 0.38 [−1.01, 2.56] <0.001
Sub-lobar 0.04 [−1.43, 0.96] −1.21 [−2.24, 0.17] <0.001 1.20 [−0.31, 3.09] 0.22 [−1.53, 3.47] 0.003
Cerebellum Anterior Lobe −0.07 [−1.14, 1.13] −0.93 [−2.09, 0.31] <0.001 1.40 [0.05, 2.44] 0.34 [−1.22, 2.04] <0.001
Occipital Lobe −0.10 [−1.02, 0.83] −1.10 [−1.98, 0.36] <0.001 0.97 [−0.31, 2.42] 0.13 [−1.29, 1.91] <0.001
Frontal-Temporal Space −0.13 [−1.19, 1.11] −0.56 [−2.23, 0.92] 0.015 1.87 [−0.40, 4.79] 0.77 [−0.98, 2.93] <0.001
Parietal Lobe −0.06 [−1.06, 0.55] −0.74 [−1.42, 0.59] <0.001 0.87 [0.17, 2.61] 0.19 [−1.07, 2.32] <0.001
Cerebellum Posterior Lobe right −0.19 [−1.70, 0.86] −0.57 [−1.67, 0.09] 0.001 0.81 [−0.58, 1.92] 0.81 [−0.58, 1.92] 0.044
Temporal Lobe −0.20 [−1.05, 0.49] −0.57 [−1.34, 0.25] <0.001 0.72 [−0.80, 2.03] 0.72 [−0.80, 2.03] 0.1
Limbic Lobe −0.08 [−1.17, 0.89] −1.15 [−2.06, 0.06] <0.001 0.19 [−1.40, 3.21] 0.19 [−1.40, 3.21] <0.001
Frontal Lobe 0.03 [−0.97, 0.75] −0.87 [−1.71, 0.44] <0.001 0.38 [−1.01, 2.56] 0.38 [−1.01, 2.56] <0.001
Sub-lobar −0.10 [−1.23, 0.68] −1.30 [−2.31, 0.37] <0.001 0.22 [−1.53, 3.47] 0.22 [−1.53, 3.47] 0.002
Cerebellum Anterior Lobe 0.01 [−1.44, 0.80] −0.80 [−2.09, 0.19] <0.001 0.34 [−1.22, 2.04] 0.34 [−1.22, 2.04] <0.001
Occipital Lobe 0.02 [−0.97, 1.28] −1.05 [−1.58, −0.07] <0.001 0.13 [−1.29, 1.91] 0.13 [−1.29, 1.91] <0.001
Frontal-Temporal Space −0.23 [−2.03, 1.50] −1.01 [−2.49, 0.53] 0.001 0.77 [−0.98, 2.93] 0.77 [−0.98, 2.93] 0.017
Parietal Lobe −0.16 [−0.87, 0.75] −0.76 [−1.58, 0.93] <0.001 0.19 [−1.07, 2.32] 0.19 [−1.07, 2.32] <0.001

Brain volume values represent the z-score of lobular volumes adjusted for age and gender. 95% CIs are indicated in parentheses. Legends: SD standard deviation; CI confidence interval.