Table 1.
Case studies of fucoidan in alternative medicine and complementary therapy: human clinical trials.
| Fucoidan Source | Cancer Type | Results | Risk of Clinically Significant Interactions | Reference |
|---|---|---|---|---|
| U. pinnatifida- | Breast cancer | No significant changes | Absent | [95] |
| Low-molecular-weight fucoidan (LMF) | Metastatic colorectal cancer (mcrc) | Improved disease control rate | Absent | [96] |
| HiQ-fucoidan from Laminaria japonica | Lung cancer | Survival rates increased by approx. 50% | Reduced the occurrence of general fatigue | [59] |
| Cladosiphon okamuranus | Colorectal cancer | Endure prolonged chemotherapy without fatigue | -Suppressed general fatigue -No suppression of diarrhea and neurotoxicity |
[97] |
| Mozuku, Cladosiphon novae-caledoniae Kylin | Advanced cancer | Decreased level of proinflammatory cytokines | Insignificant quality of life score | [98] |