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. 2022 Sep 14;23(18):10721. doi: 10.3390/ijms231810721

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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¹⁸F-FDG PET/CT axial (left), sagittal (middle) and coronal (right) fused view of right knee in patient no. 1. The first PET/CT performed at time of first relapse of GCTB (lower row) showed a focal area of intense FDG uptake (SUVmax = 21) corresponding to a lytic lesion of the medial meta-epiphyseal aspect of the right femur, showing extension to the neighbouring soft tissue. A second PET/CT scan (upper row), showed a disease relapse with an FDG avidity lower than original lesion (SUVmax = 11). A = anterior; R = right; H = high.