Figure 3.

Alternation of proteins upon treating LPS and statin in HA-TLR4-HEK293 cells. (A) Volcano plots show relative expression of identified proteins under four conditions: control, LPS, statin, and LPS–statin. Proteins were differentially altered across the different treatment conditions, e.g., statin, LPS, and both statin and LPS. (B) Principal component analysis (PCA) reveals that cross-linker treatment shows distinct discrimination among treated samples. (C) Heatmap showing relative expression across control and treatment samples with or without cross-linkers.