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. 2022 Sep 9;10(9):1808. doi: 10.3390/microorganisms10091808

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Volcano plots showing the relative protein abundance between S. aureus WC and its derived EVs. The graphs provide protein log2 fold change (log2FC) ratios between EVs and WC (EV/WC) conditions at 6 h without vancomycin (6V−) (A), 6 h with vancomycin (6V+) (B), 12 h without vancomycin (12V−) (C), and 12 h with vancomycin (12V+) (D). The vertical and horizontal dotted lines show the log2FC and significance threshold (adjusted p-value < 0.05), respectively. The results are plotted on a logarithmic scale, with negative log2FC in blue, positive log2FC in red, and nonsignificant values in grey.