Table 1.
The top ten most abundant and less abundant proteins in EVs compared to WC in all conditions that were tested. Ratios correspond to the relative abundance of proteins (log2FC) between EVs and WC (EV/WC) conditions at 6 h without vancomycin (6V−), 6 h with vancomycin (6V+), 12 h without vancomycin (12V−), and 12 h with vancomycin (12V+).
| 6V− | 6V+ | 12V− | 12V+ | ||||
|---|---|---|---|---|---|---|---|
| Protein | Ratio | Protein | Ratio | Protein | Ratio | Protein | Ratio |
| RplV | −3.08 | Hup | −4.35 | RpsJ | −3.62 | Ctc | −3.38 |
| RpsJ | −2.91 | RplK | −3.91 | RplM | −3.23 | RplQ | −3.24 |
| RpsI | −2.91 | RplQ | −3.85 | RpsE | −3.17 | RpsE | −3.07 |
| TraP | −2.87 | Ldh | −3.27 | RplR | −3.13 | Ldh | −3.04 |
| RplO | −2.82 | PyrH | −2.88 | RplL | −3.09 | AtoB | −2.99 |
| RpsE | −2.56 | Ddh | −2.68 | RplS | −2.58 | RplM | −2.54 |
| Ald | −2.43 | RplL | −2.66 | RpsK | −2.51 | Pgk | −2.37 |
| RplS | −1.78 | RpsQ | −2.65 | RpsD | −2.48 | RpsD | −2.36 |
| GluD | −1.52 | RpsI | −2.41 | Ddh | −2.4 | Ddh | −2.31 |
| RpsC | −1.29 | RplO | −2.25 | Pgk | −2.17 | AdhP | −2.17 |
| Atl | 3.61 | CyoA | 3.14 | Atl | 4.38 | * 00356 | 5.06 |
| NupC | 3.79 | Pbp4 | 3.78 | FatB | 4.66 | LpdA | 5.1 |
| CamS | 4.01 | ModA | 4.02 | SrtA | 4.71 | RecN | 5.12 |
| YidC | 4.11 | SrtA | 4.05 | SpsB | 4.78 | * 00717 | 5.16 |
| * 00356 | 4.41 | AgcS | 4.61 | PonA | 5.18 | SitA | 5.22 |
| SitA | 4.56 | PdhB | 4.8 | TcyA | 5.21 | SpsB | 5.25 |
| TcyA | 4.64 | TcyA | 4.86 | * 02587 | 5.34 | TcyA | 5.34 |
| PdhB | 4.67 | LpdA | 4.94 | FhuD | 5.38 | FhuD | 5.42 |
| FhuD | 5.05 | * 00356 | 5.17 | SitA | 5.45 | * 02587 | 5.5 |
| LpdA | 5.13 | * 02650 | 6.13 | PdhC | 6.54 | * 02650 | 5.83 |
* = SAOUHSC_ (locus tag). Example: SAOUHSC_00356.