Table 1.

Clinical practice of ovarian tissue cryopreservation.

Patient	Age(Years)	Tissue dimension (mm)	Cryopreservation method	CPA	Carrier into liquid nitrogen	Transplantation	Outcomes	Ref
ovarian abscesses N = 1	18	7–8 × 4 × 1-2	Slow freezing	DMSO	Cryogenic vials	Peritoneal pocket in the broad ligament	Follicle growth 24 weeks post-transplantation. One live birth	(15)
stage IV Hodgkin's lymphoma N = 1	25	12 × 4	Slow freezing	DMSO	Cryogenic vials	Peritoneal window beneath the ovarian hilus	Ovarian endocrine function restoration 5 months post-transplantation. One livebirth	(16)
benign ovarian surgery N = 10	16–34	4 × 4 × 1	Slow freezing	DMSO	Cryogenic vials	–	Decreased telomere length and increased senescence markers in ovarian tissue	(17)
malignant breast neoplasm N = 1	28	1–2 × 3–5  × 1–2	Slow freezing	PrOH Sucrose	Cryovial	Lateral pelvic wall	ovarian endocrine function restoration 6 months post-transplantation. One live birth	(18)
Malignant cancer N = 4	29–37	5 × 5 × 1	Slow freezing	DMSO Sucrose	Cryogenic vials	Between rectus muscle and sheath	Endocrine function was recovered 12–20 weeks post-transplantation and last for 3 months to 7 years. Four embryos for IVF	(19)
POI N = 37	28–48	5–10 × 5–10 × 1–2	Vitrification + IVA	EG Sucrose	Stainless needles of the Cryosupport	Underside serosa in one or both Fallopian tubes	Nine patients have follicle growth. Three pregnancies. Two live births	(20)
cancer survivors, POF patients N = 4	18–30	10 × 10 × 1–1.5	Vitrification	EG DMSO Sucrose	Thin metal strip	Denuded ovarian medulla	The longest functioning graft was 62 months and is still functioning. Two live births	(21)
cancer survivors, POF patient N = 9	18–30	10 × 10 × 1–1.5	Slow freeze	EG DMSO Sucrose	Cryovials	Denuded ovarian medulla	The longest functioning graft was 56 months and is still functioning. Nine live births