Table 2.
Anticancer activity of Azadirachta indica (neem), aqueous leaf extract, biosynthesized silver nanoparticles (Ag-NPs), and cisplatin (standard) in MCF-7 and HeLa cell lines.
| Sample | Concentration in mg/mL | % of Cytotoxicity MCF-7 Cell Lines |
IC50 Value in mg/mL MCF-7 Cell Lines |
% of Cytotoxicity HeLa Cell Lines |
IC50 Value in mg/mL HeLa Cell Lines |
|---|---|---|---|---|---|
| Aqueous leaf extract | 0.2 0.4 0.6 0.8 1.0 |
21.93 ± 1.95 23.61 ± 2.22 26.68 ± 1.95 32.64 ± 0.74 43.94 ± 1.81 |
1.85 ± 0.01 | 20.64 ± 0.81 22.42 ± 1.62 27.01 ± 1.95 31.54 ± 0.89 44.20 ± 1.20 |
1.76 ± 0.08 |
| Biosynthesized silver nanoparticles (Ag-NPs) |
0.2 0.4 0.6 0.8 1.0 |
45.93 ± 3.22 47.78 ± 2.66 52.68 ± 1.95 58.27 ± 2.01 65.78 ± 0.74 |
0.90 ± 0.07 | 43.20 ± 1.78 46.19 ± 2.13 51.40 ± 1.80 55.89 ± 2.26 63.20 ± 2.20 |
0.85 ± 0.01 |
| Cisplatin (standard) | 0.2 0.4 0.6 0.8 1.0 |
51.53 ± 0.95 61.13 ± 1.66 63.17 ± 2.60 65.42 ± 2.01 70.50 ± 1.99 |
0.56 ± 0.08 | 50.64 ± 1.08 62.89 ± 0.70 64.19 ± 0.40 65.20 ± 0.14 71.53 ± 0.95 |
0.45 ± 0.10 |