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Pharmacokinetic parameters obtained by analysis of rat tissues after intravenous injection of 2-PAM in IA-16/PC liposomes (dose 25 mg/kg). Results presented as mean ± standard error for five rats.
| β (min−1) |
t1/2β (min) |
|
|---|---|---|
| Plasma | 0.0296 ± 0.002 | 23.4 ± 0.02 |
| Brain | 0.0134 ± 0.001 | 51.7 ± 0.01 |
| t1/2β = ln2/β, t1/2β—elimination half-life | ||
