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. 2022 Sep 17;23(18):10901. doi: 10.3390/ijms231810901

Figure 6.

Figure 6

PPI network analysis of mRNAs predictive of pCR. (a) The 500 common mRNAs identified through ROC analysis predicative of pCR in the discovery and validation cohorts were subjected to PPI network analysis using the STRING database. Network statistics: number of nodes: 500; number of edges: 3256; average node degree: 13; avg. local clustering coefficient: 0.402; expected number of edges: 1631; PPI enrichment p-value: <1.0 × 10−16. (b) Bar graph illustrating the top 15 enriched gene ontology (GO) categories (y-axis) with network strength score presented on the x-axis.