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. 2022 Sep 23;9(3):032202. doi: 10.1117/1.NPh.9.3.032202

Table 1.

Studies that implement simultaneous wide-field and fMR imaging.

  Kennerly et al. 2005 Kennerly et al. 2012 Lake et al. 2020
Species Rats Rats Mice
Anesthesia Urethane Urethane Isoflurane
Paradigm Acute Acute Acute and chronic
Stimulus Whisker and CO2 Whisker Hind-paw
Surgery Skull thinning Skull thinning Skull thinning
Optical
Spatial resolution (μm2) 200 × 200 80 × 80 25 × 25
Temporal resolution (ms) 125 125 100
Coverage 6-mm diameter circle 6-mm diameter circle 14.5×14.5  mm2
Contrast Intrinsic oxy-/deoxy-Hb Intrinsic oxy-/deoxy-Hb Fluorescence Ca2+
Fiber bundle 50,000 50,000 2,000,000
fMRI
Spatial resolution 0.47×0.47×2.00  mm3 0.47×0.47×2.00  mm3 0.4×0.4×0.4  mm3
Temporal resolution (s) 1 or 2 1 1
Coverage Single slice Single slice 28 slices
Contrast BOLD and CBV BOLD BOLD
Scanner (T) 3 7 11.7
RF-coil Custom Custom Custom