Table 1.
Demographic and clinical characteristics of 128 patients with severe influenza A(H7N9) infection, Zhejiang, China
| Characteristics | Overall (N = 128) | Fatal patients (N = 47) | Non-fatal patients (N = 81) | Statistic | P value |
|---|---|---|---|---|---|
| Age, years, mean (s.d.) | 58·9 (14·4) | 66·5 (11·9) | 54·7 (13·8) | t = 4·79 | <0·01* |
| Sex, male, n (%) | 86 (67·2) | 33 (70·2) | 53 (65·4) | n.a. | 0·70† |
| Occupation, n (%) | n.a. | 0·09† | |||
| Farmer | 60 (46·7) | 22 (46·8) | 38 (46·9) | ||
| Homemaker or retired | 40 (31·3) | 19 (40·4) | 21 (25·9) | ||
| Others | 28 (21·9) | 6 (12·8) | 22 (27·2) | ||
| Comorbid hypertension, n (%) | 49 (38·3) | 18 (38·3) | 31 (38·3) | n.a. | 1·00† |
| Comorbid diabetes mellitus, n (%) | 26 (20·3) | 14 (29·8) | 12 (14·8) | n.a. | 0·06† |
| Comorbid cardiovascular disease, n (%) | 12 (9·4) | 2 (4·3) | 10 (12·3) | n.a. | 0·20† |
| Comorbid respiratory diseases, n (%) | 6 (4·7) | 2 (4·3) | 4 (4·9) | n.a. | 1·00† |
| Antiviral therapy: Yes, n (%) | 102 (79·7) | 37 (78·7) | 65 (80·3) | n.a. | 0·82† |
| Antiviral therapy in 48 h: Yes, n (%) | 9 (7·0) | 4 (8·5) | 5 (6·17) | n.a. | 0·72† |
| Symptom onset to first clinical visit, median (days) | 1 | 1 | 1 | χ2 = 2·91 | 0·09‡ |
| First clinical visit to admission, median (days) | 3 | 3 | 3 | χ2 = 0·91 | 0·34‡ |
| The first recorded body temperature, °C, mean (s.d.) | 38·6 (0·9) | 38·7 (0·8) | 38·6 (0·9) | t = 0·30 | 0·76* |
| WBC count at admission 109/l, mean (s.d.) | 4·9 (3·0) | 5·5 (2·9) | 4·7 (3·0) | t = 1·39 | 0·16* |
| Lymphocyte percentage at admission, %, mean (s.d.) | 16·6 (8·7) | 14·4 (9·8) | 17·7 (7·9) | t = 1·57 | 0·12* |
n.a., Not available; WBC, white blood cell.
†
By Fisher's exact test.
‡
By Kruskal-Wallis test.
*
By t test.