Table 4.
Clinical characterization of severe dengue by age group in females
| Study population | Children | Adolescents | Adults | Elderly | |||||
|---|---|---|---|---|---|---|---|---|---|
| Clinical manifestation | n/N (%) | n/N (%) | P value | n/N (%) | P value | n/N (%) | P value | n/N (%) | P value |
| Any sign of haemorrhage | 238/360 (66·1) | 19/22 (86·4) | 0·04* | 51/75 (68·0) | 0·70 | 148/223 (66·4) | 0·90 | 20/40 (50·0) | 0·02* |
| Epistaxis | 24/232 (10·3) | 6/18 (33·3) | <0·01* | 4/47 (8·5) | 0·79 | 12/147 (8·2) | 0·15 | 2/20 (10·0) | 1·00 |
| Haematuria | 32/232 (13·8) | 0/18 (0) | 0·15 | 3/47 (6·4) | 0·15 | 24/147 (16·3) | 0·14 | 5/20 (25·0) | 0·13 |
| Gingival bleeding | 23/233 (9·9) | 2/18 (11·1) | 0·69 | 5/48 (10·4) | 0·89 | 16/147 (10·9) | 0·50 | 0/20 (0) | 0·23 |
| Gastrointestinal bleeding | 11/232 (4·7) | 2/18 (11·1) | 0·21 | 2/47 (4·3) | 1·0 | 6/147 (4·1) | 0·53 | 1/20 (5·0) | 1·0 |
| Petechiae | 77/233 (33·0) | 5/18 (27·8) | 0·62 | 24/48 (50·0) | <0·01* | 42/147 (28·6) | 0·06 | 6/20 (30·0) | 0·76 |
| Positive tourniquet test | 123/234 (52·6) | 12/19 (63·2) | 0·34 | 30/50 (60·0) | 0·24 | 73/146 (50·0) | 0·31 | 8/19 (42·1) | 0·34 |
| Any signs of plasma leakage | 115/332 (34·6) | 11/21 (52·4) | 0·08 | 29/72 (40·3) | 0·26 | 65/203 (32·0) | 0·21 | 10/36 (27·8) | 0·36 |
| Haemoconcentration | 62/332 (18·7) | 4/21 (19·0) | 1·0 | 12/72 (16·7) | 0·62 | 42/203 (20·7) | 0·24 | 4/36 (11·1) | 0·26 |
| Cavity effusion | 43/332 (13·0) | 5/21 (23·8) | 0·13 | 14/72 (19·4) | 0·06 | 19/203 (9·4) | 0·01* | 5/36 (13·9) | 0·86 |
| Hypoproteinaemia | 11/332 (3·3) | 2/21 (9·5) | 0·15 | 3/72 (4·2) | 0·71 | 5/203 (2·5) | 0·28 | 1/36 (2·8) | 1·0 |
| Any neurological disorders | 6/380 (1·6) | 0/23 (0) | 1·0 | 3/78 (3·8) | 0·10 | 3/235 (1·3) | 0·68 | 0/44 (0) | 1·0 |
| Any cardiac disorders | 2/380 (0·5) | 0/23 (0) | 1·0 | 0/78 (0) | 1·0 | 2/235 (0·9) | 0·53 | 0/44 (0) | 1·0 |
n/N, Number of patients with the condition/number of patients with data available.
*
Significant P value using χ2 test.